|
| Moq: | 1KG |
| 標準パッケージ: | 1kg/バッグ25kg/ドラム |
| 配達期間: | 3～5日 |
| 支払方法: | T/T、Alibaba、PayPal |
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme compound composed of nicotinamide, ribose, phosphate, and adenosine monophosphate (AMP). It primarily acts as a coenzyme for dehydrogenases in redox reactions. In its molecule, the nicotinamide nitrogen undergoes a reversible electron-accepting oxidation state change (from 5 to 3 valences), and the para-carbon atom can undergo single-hydrogen reduction.
NAD+ acts as a carrier of hydrogen atoms and electrons in biological oxidation processes, accepting 2H+ (2H+ + 2e+) removed from metabolites and transferring it to flavoproteins. As the initiating coenzyme of the NADH oxidative respiratory chain, NAD+ acts as a hydrogen carrier in oxidative phosphorylation and plays a crucial role in cytoplasmic-mitochondrial shuttle mechanisms such as α-glycerophosphate shuttle and malate-aspartate shuttle.
1. A Core Participant in Energy Metabolism
This is NAD+'s most classic and fundamental role. NADH transports electrons into the mitochondrial electron transport chain, generating large amounts of ATP (the cell's energy currency) through oxidative phosphorylation. Without NAD+, cellular energy production stagnates.
2. An Essential Activator of Longevity Proteins
NAD+ levels directly determine deacetylases, thus affecting cellular health, aging, and lifespan.
3. DNA Repair Enzymes
When cellular DNA is damaged, PARPs are rapidly activated, consuming large amounts of NAD+ as substrates to synthesize polymers. Sufficient NAD+ is a prerequisite for effectively repairing DNA damage and preventing gene mutations and cell carcinogenesis.
4. A Regulator of Immune Cell Function
Immune cells (such as macrophages) undergo dramatic metabolic reorganization during activation and execution of immune functions, requiring large amounts of energy and biosynthetic materials. This process is highly dependent on NAD+.
NAD+ levels influence the activity of immune cells and the production of inflammatory factors, linking cellular metabolism with the immune response.
Energy production: As a key electron carrier, it helps convert food into cellular energy (ATP) in mitochondria, serving as the "power source" for life activities.
Anti-aging: It activates longevity proteins, repairs DNA damage, and maintains genome stability, acting as the "master switch" for cell repair and anti-aging.
Maintaining health: It supports the normal function of the brain, heart, muscles, and immune system, acting as a "regulator" for various physiological processes.
| Items | Standards | Results |
| Physical and chemical analysis: | ||
| Description | White powder | Conforms |
| Identification | Consistent with the control spectrum | Conforms |
| Mesh Size | Not less than 90% through 80 mesh | Conforms |
| Sodium(Na) | < 1% | 0.01% |
| Assay | ≥98% (as dry) | 98.40% |
| Purity | ≥98.0% | 99.90% |
| Loss on Drying | ≤5.0% | 3.7% |
| Ash Content | ≤1.0% | 0.02% |
| PH | 2.4-4.0 | 3.7 |
| Ethanol Solvent Residue | ≤3000mg/kg | Conforms |
| Residue analysis: | ||
| Pb | ≤0.50mg/kg | Conforms |
| As | ≤0.50mg/kg | Conforms |
| Cd | ≤0.50mg/kg | Conforms |
| Hg | ≤0.10mg/kg | Conforms |
| Microbiological: | ||
| Total Plate Count | ≤500cfu/g | 10cfu/g |
| Yeast&Mold | ≤50cfu/g | 10cfu/g |
| E.coil | Negative/10g | Conforms |
| Salmonella | Negative/10g | Conforms |
| Staphylococcus aureus | Negative/10g | Conforms |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin
|
|
| Moq: | 1KG |
| 標準パッケージ: | 1kg/バッグ25kg/ドラム |
| 配達期間: | 3～5日 |
| 支払方法: | T/T、Alibaba、PayPal |
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme compound composed of nicotinamide, ribose, phosphate, and adenosine monophosphate (AMP). It primarily acts as a coenzyme for dehydrogenases in redox reactions. In its molecule, the nicotinamide nitrogen undergoes a reversible electron-accepting oxidation state change (from 5 to 3 valences), and the para-carbon atom can undergo single-hydrogen reduction.
NAD+ acts as a carrier of hydrogen atoms and electrons in biological oxidation processes, accepting 2H+ (2H+ + 2e+) removed from metabolites and transferring it to flavoproteins. As the initiating coenzyme of the NADH oxidative respiratory chain, NAD+ acts as a hydrogen carrier in oxidative phosphorylation and plays a crucial role in cytoplasmic-mitochondrial shuttle mechanisms such as α-glycerophosphate shuttle and malate-aspartate shuttle.
1. A Core Participant in Energy Metabolism
This is NAD+'s most classic and fundamental role. NADH transports electrons into the mitochondrial electron transport chain, generating large amounts of ATP (the cell's energy currency) through oxidative phosphorylation. Without NAD+, cellular energy production stagnates.
2. An Essential Activator of Longevity Proteins
NAD+ levels directly determine deacetylases, thus affecting cellular health, aging, and lifespan.
3. DNA Repair Enzymes
When cellular DNA is damaged, PARPs are rapidly activated, consuming large amounts of NAD+ as substrates to synthesize polymers. Sufficient NAD+ is a prerequisite for effectively repairing DNA damage and preventing gene mutations and cell carcinogenesis.
4. A Regulator of Immune Cell Function
Immune cells (such as macrophages) undergo dramatic metabolic reorganization during activation and execution of immune functions, requiring large amounts of energy and biosynthetic materials. This process is highly dependent on NAD+.
NAD+ levels influence the activity of immune cells and the production of inflammatory factors, linking cellular metabolism with the immune response.
Energy production: As a key electron carrier, it helps convert food into cellular energy (ATP) in mitochondria, serving as the "power source" for life activities.
Anti-aging: It activates longevity proteins, repairs DNA damage, and maintains genome stability, acting as the "master switch" for cell repair and anti-aging.
Maintaining health: It supports the normal function of the brain, heart, muscles, and immune system, acting as a "regulator" for various physiological processes.
| Items | Standards | Results |
| Physical and chemical analysis: | ||
| Description | White powder | Conforms |
| Identification | Consistent with the control spectrum | Conforms |
| Mesh Size | Not less than 90% through 80 mesh | Conforms |
| Sodium(Na) | < 1% | 0.01% |
| Assay | ≥98% (as dry) | 98.40% |
| Purity | ≥98.0% | 99.90% |
| Loss on Drying | ≤5.0% | 3.7% |
| Ash Content | ≤1.0% | 0.02% |
| PH | 2.4-4.0 | 3.7 |
| Ethanol Solvent Residue | ≤3000mg/kg | Conforms |
| Residue analysis: | ||
| Pb | ≤0.50mg/kg | Conforms |
| As | ≤0.50mg/kg | Conforms |
| Cd | ≤0.50mg/kg | Conforms |
| Hg | ≤0.10mg/kg | Conforms |
| Microbiological: | ||
| Total Plate Count | ≤500cfu/g | 10cfu/g |
| Yeast&Mold | ≤50cfu/g | 10cfu/g |
| E.coil | Negative/10g | Conforms |
| Salmonella | Negative/10g | Conforms |
| Staphylococcus aureus | Negative/10g | Conforms |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin
