Raw Material White Powder 99.0% Uridine 5'-triphosphoric Acid Trisodium Salt 19817-92-6 Uridine 5'-triphosphate

Uridine 5'-triphosphoric Acid Trisodium Salt 

What is Uridine 5'-triphosphoric Acid Trisodium Salt ?   

Uridine-5'-triphosphate trisodium salt, also known as uridine triphosphate (UTP), has a chemical formula of C9H12N2Na3O15P3, a molecular weight of 550.09, and a CAS number of 19817-92-6. Appearance is white powder, density is 2.106g/cm³, melting point is 140°C, water solubility at room temperature is 75g/100mL, storage needs to be kept in -20°C environment.

As an intermediate for nucleotide drugs, this substance plays a role in pancreatic endocrine regulation and cell signaling. Studies have confirmed that it is involved in the xylose regeneration and rescue pathway, catalyzing xylose-1-phosphate to uridine diphosphate xylose through glucose-1-phosphate uridylyl transferase. The research team constructed a metabolic pathway containing 8 enzymes. Using ammonium bicarbonate as the starting material and driven by the ATP regeneration system, UTP at a concentration of 0.85 mmol/L can be synthesized within 3 hours and realize RNA transcription in artificial cells.

Feature

As a direct precursor for RNA biosynthesis
During the transcription process, UTP is directly involved in the elongation of the RNA chain, introducing uridylic acid into the nascent RNA chain. This is its most fundamental biological function.

Participate in the synthesis of glycogen and glycosaminoglycans
UTP is the precursor of reactive intermediates such as uridine diphosphate-glucose and uridine diphosphate-N-acetylglucosamine. These intermediates are necessary for the synthesis of glycogen (the body's energy storage form) and glycosaminoglycans (such as hyaluronic acid, chondroitin sulfate, important components of joint cartilage and skin).

Acts as energy currency and signaling molecules in cell signaling
Like ATP, UTP can also provide energy for certain biochemical reactions by hydrolyzing its high-energy phosphate bonds. In addition, UTP itself can act as a signaling molecule outside cells, activating specific purinergic receptors to regulate cell proliferation, differentiation and inflammatory responses.

Applications

molecular biology research 
In the laboratory, it is an essential raw material for the synthesis of various RNA molecules such as mRNA, siRNA, and antisense RNA. This is crucial in the study of gene function, drug development and preparation of vaccines (such as mRNA vaccines). RT-PCR and sequencing: As key components of many molecular biology test kits.

Medical field
Diagnostic Tools: In medical diagnostics, can be used to evaluate the activity of certain enzymes or as substrates for specific detection reactions.
Potential Therapeutic Applications: Its potential in liver disease (promoting glycogen synthesis), cartilage repair (as a raw material for glycosaminoglycan synthesis), and neuroprotection is being studied, but is mostly still in the research phase.

Cosmetics field
Leveraging its role as a precursor to the synthesis of hyaluronic acid and glycosaminoglycans, it can be added to high-end anti-aging skin care products. In theory, providing UTP to skin cells can promote the synthesis of these moisturizing and structural components, thereby helping to repair the skin barrier, increase skin elasticity and moisturizing.

For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin