Bulk High Quality Food/Cosmetic Grade 99% N-Acetyl-D-Glucosamine NAG N-Acetylglucosamine Powder Pure N-Acetylglucosamine

 N-Acetylglucosamine Powder

What is N-Acetylglucosamine Powder?   

N-acetylglucosamine is the basic structural unit of chitin in the exoskeleton of crustaceans. It is a white powder at room temperature with a melting point of approximately 201-204°C, readily soluble in water, and is mainly produced by fermenting glucose with Corynebacterium glutamicum RDG-2110 and corn steep liquor powder. This substance possesses anti-inflammatory, anti-tumor, and antioxidant properties.

In vivo, N-acetylglucosamine is synthesized from fructose-6-phosphate and glutamine, serving as an important precursor for the synthesis of bifidus factors. It is ultimately converted to uridine diphosphate-N-acetylglucosamine, participating in the synthesis of glycosaminoglycans and proteoglycans.

Feature

Articular Cartilage Matrix Synthesis: N-acetylglucosamine is a key precursor in the synthesis of hyaluronic acid, chondroitin sulfate, and keratinocytes, components of the articular cartilage matrix, directly replenishing the building blocks of chondrocytes. It stimulates chondrocytes to synthesize proteoglycans and collagen, promoting the self-repair and regeneration of cartilage tissue. By enhancing the water retention and elasticity of cartilage, it effectively alleviates joint wear and tear and improves joint function.

Anti-inflammatory and Immunomodulatory Effects:This component inhibits the expression of pro-inflammatory cytokines such as interleukin-1β, reducing synovial inflammation and relieving pain and swelling. It acts as a ligand for macrophage surface receptors, regulating innate immune responses and reducing tissue damage caused by excessive immunity. In gut health, it promotes the growth of beneficial bacteria, improves intestinal mucosal barrier function, and exerts a systemic immunomodulatory effect.

Skin Barrier Repair and Moisturizing:N-acetylglucosamine is an essential substrate for hyaluronic acid synthesis in the skin, increasing hyaluronic acid content in the dermis and enhancing the skin's water-locking capacity. It promotes the normal differentiation and renewal of epidermal keratinocytes, repairing damaged skin barriers. By inhibiting tyrosinase glycosylation and reducing melanin production, it has the effect of helping to brighten skin tone.

Applications

Joint and Osteoarthritis Health Supplements: Primarily used to improve osteoarthritis symptoms. As dietary supplements, they relieve joint pain and stiffness and improve mobility, often combined with ingredients such as chondroitin sulfate and MSM. Suitable for athletes, the elderly, and those with joint strain, for daily joint maintenance and aiding recovery from sports injuries. Widely used in pet nutrition for joint health in dogs and cats.

Skin Health and Beauty Applications: Added as a functional ingredient to high-end skincare products to repair the skin barrier, enhance skin hydration, and improve skin texture. In oral beauty supplements, they promote the synthesis of endogenous hyaluronic acid in the skin, improving dryness and elasticity, often combined with collagen peptides and vitamin C. In the medical aesthetics field, they are used in post-operative repair products to promote skin recovery.

Digestive and Immune Support: Dietary supplements used to improve intestinal problems such as irritable bowel syndrome and inflammatory bowel disease, working by repairing the intestinal mucosa and regulating gut microbiota. As immunomodulators, they are used to help improve symptoms associated with autoimmune diseases or to enhance immunity in the general population. In foods for special medical purposes, they are used for patients requiring enteral nutritional support.

Other biomedical research applications include: serving as a component of drug carriers or targeting molecules to improve drug bioavailability and targeting; acting as a modifying component in cartilage scaffold materials in tissue engineering to promote chondrocyte adhesion and proliferation; and being used as a prebiotic in functional foods and as a feed additive to improve gut health and growth performance in farmed animals.

For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin