| MOQ: | 1kg |
| Standard Packaging: | 1kg/bag 25kg/drum |
| Delivery Period: | 3-5days |
| Payment Method: | T/T,alibaba,paypal |
Acetyl octapeptide-1 is a linear short peptide composed of eight amino acids, with the chemical formula C50H96N20O10 and a molecular weight of 1137.42. It is a white solid. This substance has a phospholipid-like structure with hydrophilic ends and a hydrophobic center, and exhibits good solubility in pure water.
Acetyl octapeptide-1 self-assembles through intermolecular non-covalent bonds to form uniform and stable sheet-like nanofibers. As a three-dimensional cell culture scaffold, it can adhere to cell growth factors, mimicking the in vivo cellular microenvironment. It is now widely used in the production of cosmetics and health products.
Inhibiting Acetylcholine Release: Acetyl octapeptide-1 mimics the C-terminal fragment of the SNAP-25 protein, competitively inhibiting the formation of the SNARE complex involved in acetylcholine vesicle release. This reduces the release of acetylcholine from nerve endings, gently blocking the transmission of muscle contraction signals.
Reducing Dynamic Wrinkles: By reversibly relaxing facial expression muscles, it effectively reduces dynamic wrinkles caused by repeated muscle contractions, such as forehead lines, crow's feet, and frown lines. The effect is similar to botulinum toxin but is milder and non-invasive.
Improving Skin Smoothness: With reduced muscle activity, the folding of the skin surface caused by facial expressions decreases, making the skin visually smoother and firmer, and enhancing radiance due to improved local microcirculation.
High Safety and Reversibility: This peptide acts only on the neuromuscular junction of the local skin and does not enter the systemic circulation. Nerve signal transmission function is fully restored after discontinuation, with no risk of toxic accumulation.
High-end anti-wrinkle skincare products: Used as a core ingredient in serums, eye creams, face creams, and targeted treatments for dynamic wrinkles, specifically for areas with active facial muscles such as the forehead, corners of the eyes, and around the lips.
Preventive anti-aging care: Used in early anti-aging products for younger skin, preventing dynamic wrinkles from becoming static deep wrinkles. Suitable for individuals showing early signs of aging or those who wish to intervene proactively.
Combined medical aesthetic solutions and post-treatment maintenance: Used as a home maintenance product after medical aesthetic procedures such as microneedling and laser treatments to consolidate and extend the treatment effects. Can be used alternately with injectable medical aesthetic treatments to reduce treatment frequency.
Synergistic anti-aging formula: Often combined with other peptides (such as signal peptides and collagen-promoting peptides), retinol derivatives, and antioxidants to create a multi-layered anti-aging system, achieving multi-target improvement of wrinkles and skin texture.
| Items | Standards | Results |
| Physical and chemical analysis: | ||
| Description | White to off-white powder | Qualified |
| Identity by ESI-MS | Theoretical MW: 1075.2 | Qualified |
| Purity (HPLC) | ≥98% | 99.30% |
| Peptide Content(By N) | ≥80% | 92.88% |
| Water (K.F.) | ≤7% | 1.86% |
| Acetic acid content | ≤15% | 1.06% |
| Trifluoroacetic acid content | ≤1% | Negative |
| Solubility | ≥2mg/ml(H2O) | Qualified |
| Residue analysis: | ||
| Pb | ≤10ppm | <10ppm |
| As | ≤2ppm | <2ppm |
| Hg | ≤1ppm | <1ppm |
| Cd | ≤5ppm | <5ppm |
| Microbiological: | ||
| Total Plate Count | ≤1000cfu/g | Qualified |
| Yeast&Mold | ≤100cfu/g | Qualified |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin
| MOQ: | 1kg |
| Standard Packaging: | 1kg/bag 25kg/drum |
| Delivery Period: | 3-5days |
| Payment Method: | T/T,alibaba,paypal |
Acetyl octapeptide-1 is a linear short peptide composed of eight amino acids, with the chemical formula C50H96N20O10 and a molecular weight of 1137.42. It is a white solid. This substance has a phospholipid-like structure with hydrophilic ends and a hydrophobic center, and exhibits good solubility in pure water.
Acetyl octapeptide-1 self-assembles through intermolecular non-covalent bonds to form uniform and stable sheet-like nanofibers. As a three-dimensional cell culture scaffold, it can adhere to cell growth factors, mimicking the in vivo cellular microenvironment. It is now widely used in the production of cosmetics and health products.
Inhibiting Acetylcholine Release: Acetyl octapeptide-1 mimics the C-terminal fragment of the SNAP-25 protein, competitively inhibiting the formation of the SNARE complex involved in acetylcholine vesicle release. This reduces the release of acetylcholine from nerve endings, gently blocking the transmission of muscle contraction signals.
Reducing Dynamic Wrinkles: By reversibly relaxing facial expression muscles, it effectively reduces dynamic wrinkles caused by repeated muscle contractions, such as forehead lines, crow's feet, and frown lines. The effect is similar to botulinum toxin but is milder and non-invasive.
Improving Skin Smoothness: With reduced muscle activity, the folding of the skin surface caused by facial expressions decreases, making the skin visually smoother and firmer, and enhancing radiance due to improved local microcirculation.
High Safety and Reversibility: This peptide acts only on the neuromuscular junction of the local skin and does not enter the systemic circulation. Nerve signal transmission function is fully restored after discontinuation, with no risk of toxic accumulation.
High-end anti-wrinkle skincare products: Used as a core ingredient in serums, eye creams, face creams, and targeted treatments for dynamic wrinkles, specifically for areas with active facial muscles such as the forehead, corners of the eyes, and around the lips.
Preventive anti-aging care: Used in early anti-aging products for younger skin, preventing dynamic wrinkles from becoming static deep wrinkles. Suitable for individuals showing early signs of aging or those who wish to intervene proactively.
Combined medical aesthetic solutions and post-treatment maintenance: Used as a home maintenance product after medical aesthetic procedures such as microneedling and laser treatments to consolidate and extend the treatment effects. Can be used alternately with injectable medical aesthetic treatments to reduce treatment frequency.
Synergistic anti-aging formula: Often combined with other peptides (such as signal peptides and collagen-promoting peptides), retinol derivatives, and antioxidants to create a multi-layered anti-aging system, achieving multi-target improvement of wrinkles and skin texture.
| Items | Standards | Results |
| Physical and chemical analysis: | ||
| Description | White to off-white powder | Qualified |
| Identity by ESI-MS | Theoretical MW: 1075.2 | Qualified |
| Purity (HPLC) | ≥98% | 99.30% |
| Peptide Content(By N) | ≥80% | 92.88% |
| Water (K.F.) | ≤7% | 1.86% |
| Acetic acid content | ≤15% | 1.06% |
| Trifluoroacetic acid content | ≤1% | Negative |
| Solubility | ≥2mg/ml(H2O) | Qualified |
| Residue analysis: | ||
| Pb | ≤10ppm | <10ppm |
| As | ≤2ppm | <2ppm |
| Hg | ≤1ppm | <1ppm |
| Cd | ≤5ppm | <5ppm |
| Microbiological: | ||
| Total Plate Count | ≤1000cfu/g | Qualified |
| Yeast&Mold | ≤100cfu/g | Qualified |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin