Cosmetic Grade 98% Acetyl Hexapeptide-38 CAS 1400634-44-7 Acetyl Hexapeptide-38 Powder

Acetyl Hexapeptide-38

What is Acetyl Hexapeptide-38?   

Acetyl hexapeptide-38 is a synthetic peptide composed of six amino acids, acetylated to enhance its skin permeability and stability. Its molecular design mimics natural skin repair signaling fragments, enabling it to target specific cellular signaling pathways. As an emerging multifunctional active ingredient, it is widely used in high-end anti-aging skincare products, improving signs of skin aging through a multi-dimensional mechanism of action.

Feature

Stimulates Collagen Synthesis: Acetyl hexapeptide-38 activates the transforming growth factor-β signaling pathway in dermal fibroblasts, directly promoting the gene expression and synthesis of type I and type III collagen. By inhibiting collagenase activity, it reduces the degradation of existing collagen, thus bidirectionally maintaining the density and integrity of the dermal collagen network.

Enhances Skin Barrier Function: This ingredient promotes the synthesis of key skin barrier proteins such as filaggrin and naeglerin, strengthening the cohesion and structure of the stratum corneum. By regulating the composition of intercellular lipids, it improves the skin's own moisturizing ability, effectively reducing transepidermal water loss and strengthening the defense against external stimuli.

Anti-Glycation and Antioxidant Properties: Acetyl hexapeptide-38 competitively inhibits the binding of advanced glycation end products (AGEs) to cell receptors, reducing glycation damage to collagen. Simultaneously, it possesses the ability to scavenge free radicals, reducing oxidative stress damage to skin cells and the extracellular matrix, providing comprehensive anti-aging protection.

Applications

Core Ingredients in Anti-Aging Skincare: As a key active ingredient in high-efficacy anti-wrinkle products such as serums, creams, and eye creams, it improves skin laxity, static wrinkles, and lack of elasticity caused by collagen loss. It is especially suitable for early to mature skin, aiming to achieve a firmer, more defined, and youthful appearance.

Barrier Repair and Sensitive Skin Care: Added to repair products specifically designed for sensitive and fragile skin, it alleviates dryness, redness, and irritation by strengthening the skin barrier. It improves temporary barrier damage caused by over-cleansing, environmental stress, or cosmetic procedures, accelerating the skin's return to a healthy homeostasis.

Preventative and Comprehensive Anti-Aging Solutions: Used as a preventative anti-aging ingredient in daily skincare products for younger skin, it intervenes in photoaging and natural aging processes in advance, delaying the appearance of fine lines. It is often combined with other peptides (such as acetyl hexapeptide-8), vitamin A derivatives, and antioxidants to create a multi-layered, multi-target synergistic anti-aging formula.

For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin