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Pure 95% Food Grade Supplement CAS 151533-22-1 Levomefolate Calcium Calcium L-5-methyltetrahydrofolate Powder

Pure 95% Food Grade Supplement CAS 151533-22-1 Levomefolate Calcium Calcium L-5-methyltetrahydrofolate Powder

Moq: 1kg
標準パッケージ: 1kg/バッグ25kg/ドラム
配達期間: 3~5日
支払方法: T/T、アリババ、ペイパル
詳細情報
起源の場所
中国
ブランド名
SL
証明
ISO22000/ISO9001/HACCP/FDA
モデル番号
SL25120903
名前:
Levomefolateカルシウム
外観:
白色の結晶性粉末
純度:
95%
MOQ:
1kg
ブランド:
スロバニア
証明書:
ISO22000/ISO9001/HACCP
ストレージ:
一定の低温で直接太陽の光がない、よく閉じられた場所に保管してください
貯蔵寿命:
適切に保管された場合は 24 か月
製品の説明

 Levomefolate Calcium

What is Levomefolate Calcium?   

L-5-methyltetrahydrofolate calcium is a chemical substance with the molecular formula C20H23CaN7O6 and CAS number 151533-22-1. Its Chinese name is L-5-MTHF-Ca, and its English names include CALCIUM L-5-METHYLTETRAHYDROFOLATE, L-Methylfolate, calcium, etc., with trade names including Bodyfolin and Nutrifolin. This compound is the active metabolic form of folic acid and belongs to the derivatives of tetrahydrofolate calcium salt.


As a methylated form of folic acid, its molecular structure contains a complex of an L-glutamic acid group and a benzoyl group, existing as a calcium salt. Compared to ordinary folic acid, it can directly participate in one-carbon unit transfer reactions in vivo without metabolic conversion, and is mainly used in the pharmaceutical and nutritional supplement fields. Related formulations can be prepared by chemical synthesis, and some products exist in a highly stable crystalline form with good water solubility.

 

Pure 95% Food Grade Supplement CAS 151533-22-1 Levomefolate Calcium Calcium L-5-methyltetrahydrofolate Powder 0

Feature

Highly Efficient in One-Carbon Unit Metabolism: L-5-Methyltetrahydrofolate calcium acts as a direct donor of methyl groups in the body, participating in key biochemical processes such as DNA synthesis and repair, gene expression regulation, and protein methylation. It supports cardiovascular and nervous system health by maintaining the normal functioning of the homocysteine-methionine cycle, converting harmful homocysteine ​​into beneficial methionine.


Supporting Nervous System Development and Function: This active folic acid is an essential cofactor in the methylation reactions during the synthesis of neurotransmitters (such as serotonin, dopamine, and norepinephrine), crucial for maintaining mood stability and cognitive function. It plays an irreplaceable role in fetal neural tube closure and brain development throughout pregnancy, and is the most effective form of prevention of neural tube defects.


Ensuring Normal Cell Division and Proliferation: By providing the methyl groups required for the synthesis of thymine and purine nucleotides, L-5-methyltetrahydrofolate calcium ensures the fidelity of genetic material replication, supports normal red blood cell production, and the health of all rapidly regenerating tissues.


Applications

Early Pregnancy Care and Eugenics: As the preferred form of folic acid supplementation for women planning pregnancy and pregnant women (especially in early pregnancy), it effectively prevents neural tube defects in the fetus (such as spina bifida and anencephaly). It is suitable for all women of childbearing age, especially MTHFR gene mutation carriers, ensuring the fetus receives sufficient available active folic acid to support normal development.


Cardiovascular and Neurological Health Support: Used for patients with hyperhomocysteinemia to reduce the risk of cardiovascular and cerebrovascular diseases (such as stroke and coronary heart disease) and neurodegenerative diseases (such as Alzheimer's disease). As a nutritional support program for the adjunctive treatment of mood disorders such as depression and anxiety, it improves symptoms by supporting neurotransmitter synthesis.


Nutritional Intervention for Special Populations:Used for individuals with folic acid metabolism disorders (MTHFR gene mutations) and those with folic acid deficiency due to long-term use of antiepileptic drugs or methotrexate, providing a directly usable form of folic acid. In the treatment of megaloblastic anemia, it is a more effective treatment option than regular folic acid, especially suitable for patients who do not respond well to conventional folic acid.


Product Parameters


Product Name
Calcium L-5-methyltetrahydrofolate
CAS No.
151533-22-1
Test Items
Test Standard
Appearance
White Crystalline Powder
Identification
The retention time of the principle peak should conform with standard
Assay
(Anhydrous and Solvent Free)
95.0% ~ 102.0%
L-5-MTHF
72.0% ~ 82.0%
Calcium
(Anhydrous and solvent free)
7.0% ~ 8.5%
Total Related Compounds
≤2.5%
4-Aminobenzoylglutamic Acid
≤0.5%
4a-Hydroxy-5-
Methyltetrahydrofolic Acid
≤ 1.0%
(6R and 6S)-Mefox
≤ 1.0%
Tetrahydrofolic Acid
≤ 0.5%
7,8-Dihydrofolic Acid
≤ 0.5%
Folic Acid
≤ 0.5%
5,10-Methylenetetrahydrofolic
Aicd
≤ 0.5%
5-Methyltetrahydropteroic Acid
≤ 0.5%
Dimethyltetrahydrofolic Acid
≤ 0.15%
Enantiomeric Impurity
(D-5-methyItetrahydrofolate)
≤ 1.0%
Water Content
6% ~ 17.0%
Particle Size
Pass 80mesh
Bulk Density
≥ 0.2g/ml
Residue Solvents
Ethanol:≤ 5,000ppm

2-Propanol:≤ 5,000ppm
Lead(Pb)
≤1.0ppm
Arsenic(As)
≤1.0ppm
Cadmium(Cd)
≤0.5ppm
Mercury(Hg)
≤0.1ppm
Platinum
≤10.0ppm
Boron
≤50.0ppm
Chloride
≤0.5%
Total plate count
≤100cfu/g
Yeast and mold
≤100cfu/g
Salmonella
Negative
E.coli
Negative
Package & Storage
Our packing method is 1KG/Aluminium bags, 25kg/drum

For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin

製品
製品の詳細
Pure 95% Food Grade Supplement CAS 151533-22-1 Levomefolate Calcium Calcium L-5-methyltetrahydrofolate Powder
Moq: 1kg
標準パッケージ: 1kg/バッグ25kg/ドラム
配達期間: 3~5日
支払方法: T/T、アリババ、ペイパル
詳細情報
起源の場所
中国
ブランド名
SL
証明
ISO22000/ISO9001/HACCP/FDA
モデル番号
SL25120903
名前:
Levomefolateカルシウム
外観:
白色の結晶性粉末
純度:
95%
MOQ:
1kg
ブランド:
スロバニア
証明書:
ISO22000/ISO9001/HACCP
ストレージ:
一定の低温で直接太陽の光がない、よく閉じられた場所に保管してください
貯蔵寿命:
適切に保管された場合は 24 か月
最小注文数量:
1kg
パッケージの詳細:
1kg/バッグ25kg/ドラム
受渡し時間:
3~5日
支払条件:
T/T、アリババ、ペイパル
製品の説明

 Levomefolate Calcium

What is Levomefolate Calcium?   

L-5-methyltetrahydrofolate calcium is a chemical substance with the molecular formula C20H23CaN7O6 and CAS number 151533-22-1. Its Chinese name is L-5-MTHF-Ca, and its English names include CALCIUM L-5-METHYLTETRAHYDROFOLATE, L-Methylfolate, calcium, etc., with trade names including Bodyfolin and Nutrifolin. This compound is the active metabolic form of folic acid and belongs to the derivatives of tetrahydrofolate calcium salt.


As a methylated form of folic acid, its molecular structure contains a complex of an L-glutamic acid group and a benzoyl group, existing as a calcium salt. Compared to ordinary folic acid, it can directly participate in one-carbon unit transfer reactions in vivo without metabolic conversion, and is mainly used in the pharmaceutical and nutritional supplement fields. Related formulations can be prepared by chemical synthesis, and some products exist in a highly stable crystalline form with good water solubility.

 

Pure 95% Food Grade Supplement CAS 151533-22-1 Levomefolate Calcium Calcium L-5-methyltetrahydrofolate Powder 0

Feature

Highly Efficient in One-Carbon Unit Metabolism: L-5-Methyltetrahydrofolate calcium acts as a direct donor of methyl groups in the body, participating in key biochemical processes such as DNA synthesis and repair, gene expression regulation, and protein methylation. It supports cardiovascular and nervous system health by maintaining the normal functioning of the homocysteine-methionine cycle, converting harmful homocysteine ​​into beneficial methionine.


Supporting Nervous System Development and Function: This active folic acid is an essential cofactor in the methylation reactions during the synthesis of neurotransmitters (such as serotonin, dopamine, and norepinephrine), crucial for maintaining mood stability and cognitive function. It plays an irreplaceable role in fetal neural tube closure and brain development throughout pregnancy, and is the most effective form of prevention of neural tube defects.


Ensuring Normal Cell Division and Proliferation: By providing the methyl groups required for the synthesis of thymine and purine nucleotides, L-5-methyltetrahydrofolate calcium ensures the fidelity of genetic material replication, supports normal red blood cell production, and the health of all rapidly regenerating tissues.


Applications

Early Pregnancy Care and Eugenics: As the preferred form of folic acid supplementation for women planning pregnancy and pregnant women (especially in early pregnancy), it effectively prevents neural tube defects in the fetus (such as spina bifida and anencephaly). It is suitable for all women of childbearing age, especially MTHFR gene mutation carriers, ensuring the fetus receives sufficient available active folic acid to support normal development.


Cardiovascular and Neurological Health Support: Used for patients with hyperhomocysteinemia to reduce the risk of cardiovascular and cerebrovascular diseases (such as stroke and coronary heart disease) and neurodegenerative diseases (such as Alzheimer's disease). As a nutritional support program for the adjunctive treatment of mood disorders such as depression and anxiety, it improves symptoms by supporting neurotransmitter synthesis.


Nutritional Intervention for Special Populations:Used for individuals with folic acid metabolism disorders (MTHFR gene mutations) and those with folic acid deficiency due to long-term use of antiepileptic drugs or methotrexate, providing a directly usable form of folic acid. In the treatment of megaloblastic anemia, it is a more effective treatment option than regular folic acid, especially suitable for patients who do not respond well to conventional folic acid.


Product Parameters


Product Name
Calcium L-5-methyltetrahydrofolate
CAS No.
151533-22-1
Test Items
Test Standard
Appearance
White Crystalline Powder
Identification
The retention time of the principle peak should conform with standard
Assay
(Anhydrous and Solvent Free)
95.0% ~ 102.0%
L-5-MTHF
72.0% ~ 82.0%
Calcium
(Anhydrous and solvent free)
7.0% ~ 8.5%
Total Related Compounds
≤2.5%
4-Aminobenzoylglutamic Acid
≤0.5%
4a-Hydroxy-5-
Methyltetrahydrofolic Acid
≤ 1.0%
(6R and 6S)-Mefox
≤ 1.0%
Tetrahydrofolic Acid
≤ 0.5%
7,8-Dihydrofolic Acid
≤ 0.5%
Folic Acid
≤ 0.5%
5,10-Methylenetetrahydrofolic
Aicd
≤ 0.5%
5-Methyltetrahydropteroic Acid
≤ 0.5%
Dimethyltetrahydrofolic Acid
≤ 0.15%
Enantiomeric Impurity
(D-5-methyItetrahydrofolate)
≤ 1.0%
Water Content
6% ~ 17.0%
Particle Size
Pass 80mesh
Bulk Density
≥ 0.2g/ml
Residue Solvents
Ethanol:≤ 5,000ppm

2-Propanol:≤ 5,000ppm
Lead(Pb)
≤1.0ppm
Arsenic(As)
≤1.0ppm
Cadmium(Cd)
≤0.5ppm
Mercury(Hg)
≤0.1ppm
Platinum
≤10.0ppm
Boron
≤50.0ppm
Chloride
≤0.5%
Total plate count
≤100cfu/g
Yeast and mold
≤100cfu/g
Salmonella
Negative
E.coli
Negative
Package & Storage
Our packing method is 1KG/Aluminium bags, 25kg/drum

For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin