2,3,5,6-Tetramethylpyrazine 98% Ligustrazine Powder CAS 1124-11-4 for Flavoring and Pharmaceutical Use

   Ligustrazine Powder

What is Ligustrazine Powder?   

Tetramethylpyrazine is a natural active alkaloid extracted from the umbelliferous plant Ligusticum chuanxiong. Its chemical name is tetramethylpyrazine, and it is one of the main active components responsible for the pharmacological effects of Ligusticum chuanxiong. When used as a food additive, it is usually present in synthetic or high-purity extract form, meeting national food safety standards. In traditional Chinese medicine theory, it is classified as a "blood-activating and qi-regulating" substance. Modern research has confirmed that it possesses multiple biological activities, including improving microcirculation, anti-oxidation, and neuroprotection.

Feature

Improving Microcirculation and Blood Flow: Ligustrazine can dilate arterioles and capillaries, inhibit abnormal platelet aggregation, and reduce blood viscosity, thereby significantly improving blood perfusion of tissues and organs. It protects vascular endothelial function and maintains hemodynamic stability by regulating the balance of nitric oxide and endothelin.

Antioxidant and Anti-inflammatory Properties: Ligustrazine has the ability to scavenge free radicals, inhibit lipid peroxidation, and reduce oxidative stress damage to cells and blood vessels. It can downregulate the activity of inflammatory pathways such as nuclear factor κB, reduce the release of pro-inflammatory factors such as tumor necrosis factor-α and interleukin-6, and alleviate chronic inflammation.

Neuroprotection and Cognitive Support: This component can cross the blood-brain barrier, increase cerebral blood flow, and improve brain energy metabolism. It can inhibit glutamate excitotoxicity, reduce neuronal apoptosis, and promote the expression of neurotrophic factors, showing protective potential against ischemic brain injury and neurodegenerative diseases.

Applications

Functional Foods and Health Foods: As a core ingredient in health foods that improve blood circulation, it is used to help regulate blood pressure, relieve cold hands and feet, and improve eye fatigue. Added to functional foods with "brain-boosting" claims, it supports memory, attention, and cognitive function, suitable for middle-aged and elderly people and those engaged in mental work.

Cardiovascular Health Support Products: Used to develop specific dietary supplements to help maintain healthy blood pressure and prevent atherosclerosis. As an auxiliary ingredient in sports nutrition products, it helps relieve post-exercise fatigue and accelerate recovery by improving blood flow and oxygen supply.

Modern Applications of Traditional Functions: As an active ingredient in food-medicine homology products, it is used to develop modern convenient dosage forms with "blood-activating and qi-regulating" effects, such as solid beverages and compressed candies. In products targeting women's health, it is used to relieve discomfort caused by poor blood circulation.

Exploration of Special Medical Uses: In foods for special medical uses, its nutritional support for stroke rehabilitation and patients with chronic cerebral ischemia is being studied. It is also being developed and applied as a potential food antioxidant and natural preservative.

Product Parameters

For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin