| MOQ: | 1kg |
| Standard Packaging: | 1kg/bag 25kg/drum |
| Delivery Period: | 3-5days |
| Payment Method: | T/T,alibaba,paypal |
10-Hydroxy-2-decenoic acid (royal jelly acid) is a carboxylic acid organic compound with the molecular formula C10H18O3, a molecular weight of 186.25, and CAS number 14113-05-4. This compound is a unique component of royal jelly, with a natural content of 1.4%-2.4%. It possesses antibacterial, anti-inflammatory, antioxidant, and metabolic regulating biological activities. It can alleviate neonicotinoid-induced liver damage and reduce hepatotoxicity by regulating the intestinal microecological balance.
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Anti-inflammatory and Immunosuppressive Effects: Berberine inhibits the release of key inflammatory factors such as tumor necrosis factor-α and interleukin-1β from macrophages and blocks the activation of inflammatory signaling pathways such as NF-κB. It can regulate T lymphocyte function, reduce autoantibody production, and alleviate excessive immune responses.
Analgesic and Antipyretic Effects: This component produces a central analgesic effect by inhibiting central prostaglandin synthesis and bradykinin release. It can regulate the hypothalamic temperature set point and counteract the febrile response caused by endotoxins.
Antibacterial and Antiviral Effects: Berberine has an inhibitory effect on common pathogenic bacteria such as Staphylococcus aureus and Streptococcus, possibly by disrupting bacterial biofilm structures. Studies show that it has a mild inhibitory effect on influenza viruses and herpesviruses.
Anti-fibrotic and Organ Protection: By inhibiting the transforming growth factor-β1/Smad pathway, it reduces collagen deposition and slows the fibrotic process in organs such as the liver and lungs. Its antioxidant properties help reduce tissue ischemia-reperfusion injury.
Treatment of Inflammatory and Immunological Diseases: Used as a prescription drug ingredient in the treatment of autoimmune diseases such as rheumatoid arthritis and ankylosing spondylitis, often in combination with drugs such as methotrexate. Also used as adjunctive therapy for bacterial inflammations such as acute tonsillitis and pelvic inflammatory disease.
Analgesic and Antipyretic Applications: Used as adjunctive analgesia to relieve moderate to severe pain such as postoperative pain and cancer pain. Also used as a heat-clearing ingredient in traditional cold and fever formulas to improve symptoms such as fever and sore throat.
Gynecological and Dermatological Applications: Developed as suppositories or lotions for gynecological inflammations (such as cervicitis and vaginitis), utilizing its antibacterial and anti-inflammatory properties. Used in topical preparations for skin inflammations such as eczema and contact dermatitis.
Liver Disease Adjunctive and Research: Researched as an adjunct ingredient in anti-liver fibrosis drugs, suitable for adjunctive management of chronic hepatitis and alcoholic liver disease. Used as a tool drug in basic research on immunosuppressive mechanisms and pain pathways.
| ITEM | SPECIFICATION |
| Physical Description | |
| Appearance | Yellow Powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Particle size | 95%-99%% through 80 mesh |
| Chemical Tests | |
| Palmatine | ≥98% |
| Loss on drying | ≤1.0% |
| Ash | ≤1.0 % |
| Total Heavy Metals | ≤10 ppm |
| Cadmium (Cd) | ≤1 ppm |
| Mercury (Hg) | ≤1 ppm |
| Lead (Pb) | ≤2 ppm |
| Arsenic (As) | ≤2ppm |
| Microbiology | |
| Total plate count | ≤1000 CFU/g |
| Yeast & mold | ≤100 CFU /g |
| E.coli | Negative |
| Salmonella | Negative |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin
| MOQ: | 1kg |
| Standard Packaging: | 1kg/bag 25kg/drum |
| Delivery Period: | 3-5days |
| Payment Method: | T/T,alibaba,paypal |
10-Hydroxy-2-decenoic acid (royal jelly acid) is a carboxylic acid organic compound with the molecular formula C10H18O3, a molecular weight of 186.25, and CAS number 14113-05-4. This compound is a unique component of royal jelly, with a natural content of 1.4%-2.4%. It possesses antibacterial, anti-inflammatory, antioxidant, and metabolic regulating biological activities. It can alleviate neonicotinoid-induced liver damage and reduce hepatotoxicity by regulating the intestinal microecological balance.
![]()
Anti-inflammatory and Immunosuppressive Effects: Berberine inhibits the release of key inflammatory factors such as tumor necrosis factor-α and interleukin-1β from macrophages and blocks the activation of inflammatory signaling pathways such as NF-κB. It can regulate T lymphocyte function, reduce autoantibody production, and alleviate excessive immune responses.
Analgesic and Antipyretic Effects: This component produces a central analgesic effect by inhibiting central prostaglandin synthesis and bradykinin release. It can regulate the hypothalamic temperature set point and counteract the febrile response caused by endotoxins.
Antibacterial and Antiviral Effects: Berberine has an inhibitory effect on common pathogenic bacteria such as Staphylococcus aureus and Streptococcus, possibly by disrupting bacterial biofilm structures. Studies show that it has a mild inhibitory effect on influenza viruses and herpesviruses.
Anti-fibrotic and Organ Protection: By inhibiting the transforming growth factor-β1/Smad pathway, it reduces collagen deposition and slows the fibrotic process in organs such as the liver and lungs. Its antioxidant properties help reduce tissue ischemia-reperfusion injury.
Treatment of Inflammatory and Immunological Diseases: Used as a prescription drug ingredient in the treatment of autoimmune diseases such as rheumatoid arthritis and ankylosing spondylitis, often in combination with drugs such as methotrexate. Also used as adjunctive therapy for bacterial inflammations such as acute tonsillitis and pelvic inflammatory disease.
Analgesic and Antipyretic Applications: Used as adjunctive analgesia to relieve moderate to severe pain such as postoperative pain and cancer pain. Also used as a heat-clearing ingredient in traditional cold and fever formulas to improve symptoms such as fever and sore throat.
Gynecological and Dermatological Applications: Developed as suppositories or lotions for gynecological inflammations (such as cervicitis and vaginitis), utilizing its antibacterial and anti-inflammatory properties. Used in topical preparations for skin inflammations such as eczema and contact dermatitis.
Liver Disease Adjunctive and Research: Researched as an adjunct ingredient in anti-liver fibrosis drugs, suitable for adjunctive management of chronic hepatitis and alcoholic liver disease. Used as a tool drug in basic research on immunosuppressive mechanisms and pain pathways.
| ITEM | SPECIFICATION |
| Physical Description | |
| Appearance | Yellow Powder |
| Odor | Characteristic |
| Taste | Characteristic |
| Particle size | 95%-99%% through 80 mesh |
| Chemical Tests | |
| Palmatine | ≥98% |
| Loss on drying | ≤1.0% |
| Ash | ≤1.0 % |
| Total Heavy Metals | ≤10 ppm |
| Cadmium (Cd) | ≤1 ppm |
| Mercury (Hg) | ≤1 ppm |
| Lead (Pb) | ≤2 ppm |
| Arsenic (As) | ≤2ppm |
| Microbiology | |
| Total plate count | ≤1000 CFU/g |
| Yeast & mold | ≤100 CFU /g |
| E.coli | Negative |
| Salmonella | Negative |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin