|
| MOQ: | 1กก |
| บรรจุภัณฑ์มาตรฐาน: | 1kg/bag 25kg/drum |
| ระยะเวลาการส่งมอบ: | 3-5 วัน |
| วิธีการชำระเงิน: | ที/ที, อาลีบาบา, เพย์พาล |
Vitamin D3, also known as cholecalciferol, is a type of vitamin D. Cholecalciferol is formed from 7-dehydrocholesterol, the product of cholesterol dehydrogenation, when exposed to ultraviolet light. Therefore, the vitamin D precursor for cholecalciferol is 7-dehydrocholesterol.
Vitamin D is a fat-soluble vitamin and is also considered a precursor to hormones that act on calcium and phosphorus metabolism. It is closely related to sunlight and is therefore also called the "sunshine vitamin." Vitamin D is a collective term for a group of complexes with identical A, B, C, and D ring structures but different side chains. The structures of the A, B, C, and D rings are derived from the cyclopentanenylphenanthrene ring structure. At least 10 types of vitamin D are currently known, but the most important are vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).
Regulating Calcium and Phosphorus Metabolism and Bone Health: Vitamin D3 promotes the active absorption of calcium and phosphorus in the small intestine, increasing blood calcium and phosphorus concentrations and providing the raw materials for bone mineralization. It directly stimulates osteoblast activity, promoting bone matrix maturation and calcium salt deposition, while maintaining stable blood calcium levels through negative feedback regulation. Deficiency can lead to rickets in children and osteomalacia in adults, and exacerbates the risk of osteoporosis.
Immune Regulation and Anti-inflammation: Vitamin D3 regulates the differentiation and function of immune cells, enhancing the innate immune system's defense against pathogens. It can inhibit overactive acquired immune responses, reduce the production of pro-inflammatory cytokines, and has potential regulatory effects on autoimmune diseases. Its receptors are widely present on immune cells, indicating its crucial role in immune homeostasis.
Affecting Cell Proliferation and Differentiation: Vitamin D3 regulates cell cycle progression by activating the expression of specific genes, inhibiting abnormal proliferation and promoting normal differentiation. This mechanism is particularly important in maintaining the health of tissues such as skin and intestinal epithelium, and forms the basis for research in cancer prevention. It can also affect neuromuscular function, improving muscle strength and balance.
Prevention and Treatment of Bone-Related Diseases: As a basic supplement, it is used to prevent and treat vitamin D deficiency, rickets, osteomalacia, and osteoporosis, often in combination with calcium supplements. It is used for fall prevention in the elderly, reducing fracture risk by improving muscle function. It is a core medication in the treatment of secondary hyperparathyroidism in chronic kidney disease.
Health Support for Specific Populations:Routine preventative supplementation for infants, pregnant women, breastfeeding women, and the elderly, due to insufficient synthesis capacity or increased needs in these groups. Targeted nutritional interventions for vegetarians, those lacking sunlight, and obese individuals to correct underlying vitamin D deficiency. It serves as an adjunct management tool for patients with recurrent respiratory infections and autoimmune diseases, providing support for immune function regulation.
Chronic Disease Risk Intervention: In cardiovascular health, it is used to help improve risk factors for diseases such as hypertension and arteriosclerosis. It improves insulin sensitivity as part of comprehensive management strategies for metabolic diseases such as polycystic ovary syndrome and diabetes. It shows potential value in cancer prevention and adjunctive therapy research, but more clinical evidence is needed to support this.
Chronic Disease Risk Intervention: In the field of cardiovascular health, it is used to help improve risk factors for diseases such as hypertension and arteriosclerosis. It is also used as part of comprehensive management strategies for metabolic diseases such as polycystic ovary syndrome and diabetes. Food fortification and livestock applications: Added as a nutritional fortifier to foods such as milk, milk powder, and grains to broaden population accessibility. In livestock farming, it is used as a feed additive to improve bone health, production performance, and product quality in animals and poultry.
| Items | Standards | Results |
| Physical and chemical analysis: | ||
| Description | Off White to light brown powder | Off White powder |
| Identification | The retention time of the principal peak conforms to which in the reference solution | Qualified |
| Mesh Size | 100% pass No.40 ≥90% pass No.60 ≥45% pass No.100 |
Qualified |
| Assay | ≥100,000IU/g | 521,000IU/g |
| Loss on Drying | ≤5% | 3.9% |
| Pesticides | Complies with USP<561> | Qualified |
| Residue analysis: | ||
| Heavy Metal(as Pb) | ≤10ppm | <10ppm |
| Pb | ≤0.5ppm | <0.5ppm |
| As | ≤0.5ppm | <0.5ppm |
| Hg | ≤0.1ppm | <0.1ppm |
| Cd | ≤0.1ppm | <0.1ppm |
| Microbiological: | ||
| Total Plate Count | ≤1000cfu/g | <100cfu/g |
| Yeast&Mold | ≤100cfu/g | <10cfu/g |
| Enterobacterial | ≤10cfu/g | <10cfu/g |
| Salmonella | Negative/25g | Qualified |
| Escherichia coli | Negative/10g | Qualified |
| Staphylococcus aureus | Negative/10g | Qualified |
| Pseudomonas aeruginosa | Negative/10g | Qualified |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin
|
|
| MOQ: | 1กก |
| บรรจุภัณฑ์มาตรฐาน: | 1kg/bag 25kg/drum |
| ระยะเวลาการส่งมอบ: | 3-5 วัน |
| วิธีการชำระเงิน: | ที/ที, อาลีบาบา, เพย์พาล |
Vitamin D3, also known as cholecalciferol, is a type of vitamin D. Cholecalciferol is formed from 7-dehydrocholesterol, the product of cholesterol dehydrogenation, when exposed to ultraviolet light. Therefore, the vitamin D precursor for cholecalciferol is 7-dehydrocholesterol.
Vitamin D is a fat-soluble vitamin and is also considered a precursor to hormones that act on calcium and phosphorus metabolism. It is closely related to sunlight and is therefore also called the "sunshine vitamin." Vitamin D is a collective term for a group of complexes with identical A, B, C, and D ring structures but different side chains. The structures of the A, B, C, and D rings are derived from the cyclopentanenylphenanthrene ring structure. At least 10 types of vitamin D are currently known, but the most important are vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).
Regulating Calcium and Phosphorus Metabolism and Bone Health: Vitamin D3 promotes the active absorption of calcium and phosphorus in the small intestine, increasing blood calcium and phosphorus concentrations and providing the raw materials for bone mineralization. It directly stimulates osteoblast activity, promoting bone matrix maturation and calcium salt deposition, while maintaining stable blood calcium levels through negative feedback regulation. Deficiency can lead to rickets in children and osteomalacia in adults, and exacerbates the risk of osteoporosis.
Immune Regulation and Anti-inflammation: Vitamin D3 regulates the differentiation and function of immune cells, enhancing the innate immune system's defense against pathogens. It can inhibit overactive acquired immune responses, reduce the production of pro-inflammatory cytokines, and has potential regulatory effects on autoimmune diseases. Its receptors are widely present on immune cells, indicating its crucial role in immune homeostasis.
Affecting Cell Proliferation and Differentiation: Vitamin D3 regulates cell cycle progression by activating the expression of specific genes, inhibiting abnormal proliferation and promoting normal differentiation. This mechanism is particularly important in maintaining the health of tissues such as skin and intestinal epithelium, and forms the basis for research in cancer prevention. It can also affect neuromuscular function, improving muscle strength and balance.
Prevention and Treatment of Bone-Related Diseases: As a basic supplement, it is used to prevent and treat vitamin D deficiency, rickets, osteomalacia, and osteoporosis, often in combination with calcium supplements. It is used for fall prevention in the elderly, reducing fracture risk by improving muscle function. It is a core medication in the treatment of secondary hyperparathyroidism in chronic kidney disease.
Health Support for Specific Populations:Routine preventative supplementation for infants, pregnant women, breastfeeding women, and the elderly, due to insufficient synthesis capacity or increased needs in these groups. Targeted nutritional interventions for vegetarians, those lacking sunlight, and obese individuals to correct underlying vitamin D deficiency. It serves as an adjunct management tool for patients with recurrent respiratory infections and autoimmune diseases, providing support for immune function regulation.
Chronic Disease Risk Intervention: In cardiovascular health, it is used to help improve risk factors for diseases such as hypertension and arteriosclerosis. It improves insulin sensitivity as part of comprehensive management strategies for metabolic diseases such as polycystic ovary syndrome and diabetes. It shows potential value in cancer prevention and adjunctive therapy research, but more clinical evidence is needed to support this.
Chronic Disease Risk Intervention: In the field of cardiovascular health, it is used to help improve risk factors for diseases such as hypertension and arteriosclerosis. It is also used as part of comprehensive management strategies for metabolic diseases such as polycystic ovary syndrome and diabetes. Food fortification and livestock applications: Added as a nutritional fortifier to foods such as milk, milk powder, and grains to broaden population accessibility. In livestock farming, it is used as a feed additive to improve bone health, production performance, and product quality in animals and poultry.
| Items | Standards | Results |
| Physical and chemical analysis: | ||
| Description | Off White to light brown powder | Off White powder |
| Identification | The retention time of the principal peak conforms to which in the reference solution | Qualified |
| Mesh Size | 100% pass No.40 ≥90% pass No.60 ≥45% pass No.100 |
Qualified |
| Assay | ≥100,000IU/g | 521,000IU/g |
| Loss on Drying | ≤5% | 3.9% |
| Pesticides | Complies with USP<561> | Qualified |
| Residue analysis: | ||
| Heavy Metal(as Pb) | ≤10ppm | <10ppm |
| Pb | ≤0.5ppm | <0.5ppm |
| As | ≤0.5ppm | <0.5ppm |
| Hg | ≤0.1ppm | <0.1ppm |
| Cd | ≤0.1ppm | <0.1ppm |
| Microbiological: | ||
| Total Plate Count | ≤1000cfu/g | <100cfu/g |
| Yeast&Mold | ≤100cfu/g | <10cfu/g |
| Enterobacterial | ≤10cfu/g | <10cfu/g |
| Salmonella | Negative/25g | Qualified |
| Escherichia coli | Negative/10g | Qualified |
| Staphylococcus aureus | Negative/10g | Qualified |
| Pseudomonas aeruginosa | Negative/10g | Qualified |
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin
