NAG N-Acetylglucosamine N-Acetyl Glucosamine CAS 7512-17-6 N-Acetyl-D-Glucosamine Powder

N-Acetyl Glucosamine  

What is N-Acetyl Glucosamine?   

N-acetylglucosamine, with the chemical formula C8H15NO6, molecular weight 221.21, and CAS number 7512-17-6, is the basic structural unit of chitin in the exoskeleton of crustaceans. It is a white powder at room temperature with a melting point of approximately 201-204°C, readily soluble in water, and is mainly produced through fermentation of glucose by Corynebacterium glutamicum RDG-2110 and corn steep liquor powder. This substance possesses anti-inflammatory, anti-tumor, and antioxidant properties. Clinically, it is used to treat osteoarthritis and rheumatoid arthritis, enhances the function of the human immune system, inhibits cancer cell growth, and has an adjuvant therapeutic effect on cancer and malignant tumors. It is also used as a food antioxidant, an infant food additive, and a sweetener for diabetic patients.

In vivo, N-acetylglucosamine is synthesized from fructose-6-phosphate and glutamine, serving as an important precursor for the synthesis of bifidus factor. It is ultimately converted to uridine diphosphate-N-acetylglucosamine, participating in the synthesis of glycosaminoglycans and proteoglycans. Its sulfate or hydrochloride forms are often used in combination with chondroitin sulfate.

Feature

Repair and protect articular cartilage 
It provides chondrocytes with the raw materials needed to synthesize proteoglycans and collagen, the main components of the cartilage matrix.

Promotes skin health and hydration
It is a precursor for the synthesis of hyaluronic acid in the skin. Hyaluronic acid is a powerful moisturizing factor that can lock in a large amount of moisture, making the skin plump and hydrated. It helps maintain the integrity and elasticity of the skin barrier.

anti-inflammatory effect
Research shows that N-acetylglucosamine can exert a certain anti-inflammatory effect by regulating the activity of immune cells, which is beneficial to alleviating the inflammatory state of arthritis.

Support digestive tract health
It helps form and protect the mucus layer lining the gut, potentially beneficial in maintaining a healthy gut barrier

Applications

Adjuvant treatment for osteoarthritis
As a dietary supplement, it is widely used to relieve pain, stiffness, and functional limitations caused by osteoarthritis, especially knee arthritis. Many clinical studies have shown that long-term use can improve joint function and slow down the narrowing of joint spaces.

Joint health and sports nutrition
Used for daily joint maintenance of middle-aged and elderly people to prevent or delay joint degenerative changes. Used by athletes and fitness enthusiasts to protect joints from excessive wear and tear during high-intensity training.

Skin care and beauty
Added to high-end skin care products (such as essences and creams), it aims to improve the skin's own moisturizing ability, improve fine lines, and increase skin elasticity and gloss.

Adjunctive management of inflammatory bowel disease
In some studies, it has been explored as an aid in improving the symptoms of Crohn's disease and ulcerative colitis, mainly utilizing its protective effect on the intestinal mucosa.

For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin